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fni [2017-8-11 16:0:3]
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fni [2017-8-11 16:0:3]

isopentenyl diphosphate isomerase, last (8th) step in the MEP pathway of isoprenoid biosynthesis
locus
BSU22870
pI
6.10
mw
22.45 kDa
protein length
212 aa Sequence Blast
gene length
636 bp Sequence Blast
function
MEP pathway of isoprenoid biosynthesis
product
isopentenyl diphosphate isomerase
essential
no
ec
5.3.3.2
synonyms
ypgA, idi

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.3|Biosynthesis of isoprenoids]
  • Gene

    Coordinates
    2,393,602 → 2,394,651

    The protein

    Catalyzed reaction/ biological activity

  • Isopentenyl diphosphate = dimethylallyl diphosphate (according to Swiss-Prot)
  • Protein family

  • IPP isomerase type 2 family (according to Swiss-Prot)
  • Structure

  • [PDB|1P0N] (complex with FMN)
  • [PDB|1P0K]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60|cmk]-[gene|7C36409F155E4C91CEE902FE6937571BD0C50128|ypfD]-[gene|E91624382EC3DAABFB3123CDA818B4BEF745ACE6|fni]
    description
    [pubmed|22383849]
    view in new tab

    genes
    [gene|7C36409F155E4C91CEE902FE6937571BD0C50128|ypfD]-[gene|E91624382EC3DAABFB3123CDA818B4BEF745ACE6|fni]
    description
    [pubmed|22383849]
    view in new tab

    genes
    [gene|C194336ED96FA844FFE9FB43BE59ADC5D6DDB3BE|motI]-[gene|3459BA0CDAABC288ADF97B111F78C7EAC184840D|ypfB]-[gene|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60|cmk]-[gene|7C36409F155E4C91CEE902FE6937571BD0C50128|ypfD]-[gene|E91624382EC3DAABFB3123CDA818B4BEF745ACE6|fni]
    description
    [pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-A420 (ypgA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/420 NBRP B. subtilis, Japan]
  • References

  • 12798687,17458547,14745175,23840410